COVID vaccination in pregnancy may benefit both moms and infants CIDRAP

Pregnant women can reduce their infant's risk of COVID-related hospitalization by receiving at least two doses of an mRNA vaccine, which are highly effective against maternal Delta variant infection and moderately effective against maternal and infant Omicron infection, suggests a study published yesterday in BMJ. A third (booster) dose offered added protection against Omicron.

‘No one really wants to talk about COVID anymore,’ the WHO’s pandemic lead laments. But the ‘worst case’ possibility of a new coronavirus exists “Omicron can cause severe disease” and “is not nature’s vaccine,” experts warned, raising concerns that evolution could produce a more dangerous variant—or a new coronavirus altogether. YahooFinance

... “until no one is at risk, everyone is at risk” of a disease that continues to evolve and affect different countries to different extents, Maria Van Kerkhove, technical lead for COVID-19 at the WHO, added.

Two-dose COVID vaccine efficacy durable against severe Omicron but drops in elderly

Overall two-dose vaccine effectiveness (VE) against Omicron variant-related hospitalization or death remained above 70% for at least 6 months among adults in Hong Kong but dropped to below 62% in those aged 80 and older, necessitating a third dose, finds a case-control study published today in JAMA Network Open.

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